Listar por autor "Grilló Dolset, María Jesús"
Mostrando ítems 1-20 de 22
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Brucella abortus ornithine lipids are dispensable outer membrane components devoid of a marked pathogen-associated molecular pattern
Palacios Chaves, Leyre; Conde Álvarez, Raquel; Gil Ramírez, Yolanda
; Zúñiga Ripa, Amaia; Barquero-Calvo, Elías; Chacón Díaz, Carlos; Chaves Olarte, Esteban; Arce Gorvel, Vilma; Gorvel, Jean-Pierre; Moreno, Edgardo; Miguel, María Jesús de; Grilló Dolset, María Jesús; Moriyón Uría, Ignacio; Iriarte, Maite (Public Library of Science, 2011)
Artículo / Artikulua 
The brucellae are alpha-Proteobacteria facultative intracellular parasites that cause an important zoonosis. These bacteria escape early detection by innate immunity, an ability associated to the absence of marked ... -
Brucella melitensis wzm/wzt system: changes in the bacterial envelope lead to improved rev1Δwzm vaccine properties
Mena Bueno, Sara; Poveda Urkixo, Irati; Irazoki, Oihane; Palacios Chaves, Leyre; Cava, Felipe; Zabalza Baranguá, Ana; Grilló Dolset, María Jesús (Frontiers Media, 2022)
Artículo / Artikulua
The lipopolysaccharide (LPS) O-polysaccharide (O-PS) is the main virulence factor in Brucella. After synthesis in the cytoplasmic membrane, O-PS is exported to the periplasm by the Wzm/Wzt system, where it is assembled ... -
Brucellosis vaccines: assessment of brucella melitensis lipopolysaccharide rough mutants defective in core and O-polysaccharide synthesis and export
González, David; Grilló Dolset, María Jesús; Miguel, María Jesús de; Ali, Tara; Arce Gorvel, Vilma; Delrue, Rose May; Conde Álvarez, Raquel; Muñoz Álvaro, Pilar María; López Goñi, Ignacio; Iriarte, Maite; Marín, Clara M.; Weintraub, Andrej; Widmalm, Goeran; Zygmunt, Michel; Letesson, Jean-Jacques; Gorvel, Jean-Pierre; Blasco, José María; Moriyón Uría, Ignacio (Public Library of Science, 2008)
Artículo / Artikulua
Background: The brucellae are facultative intracellular bacteria that cause brucellosis, one of the major neglected zoonoses. In endemic areas, vaccination is the only effective way to control this disease. Brucella ... -
BvrR/BvrS-controlled outer membrane proteins Omp3a and Omp3b are not essential for Brucella abortus virulence
(American Society for Microbiology, 2007) Artículo / Artikulua
The Brucella abortus two-component regulatory system BvrR/BvrS controls the expression of outer membrane proteins (Omp) Omp3a (Omp25) and Omp3b (Omp22). Disruption of bvrS or bvrR generates avirulent mutants with altered ... -
Deletion of the GI-2 integrase and the wbkA flanking transposase improves the stability of Brucella melitensis Rev 1 vaccine
Mancilla, Marcos; Grilló Dolset, María Jesús; Miguel López, María Jesús de; López Goñi, Ignacio; San Román Aberasturi, Beatriz 
; Zabalza Baranguá, Ana ; Moriyón Uría, Ignacio (BioMed Central, 2013)
Artículo / Artikulua
Brucella melitensis Rev 1 is the best vaccine available for the prophylaxis of small ruminant brucellosis and, indirectly, for reducing human brucellosis. However, Rev 1 shows anomalously high rates of spontaneous dissociation ... -
Desarrollo de vacunas marcadas con GFP frente a la brucelosis ovina y tests diagnósticos asociados
Zabalza Baranguá, Ana (2017)
Tesis doctoral / Doktoretza tesia
La brucelosis es una zoonosis extendida mundialmente con importantes repercusiones económicas y sanitarias, cuya principal fuente de infección para el ser humano son los pequeños rumiantes infectados por Brucella melitensis. ... -
Development of a selective culture medium for primary isolation of the main Brucella species
Miguel López, María Jesús de; Marín, Clara M.; Muñoz Álvaro, Pilar María; Dieste, L.; Grilló Dolset, María Jesús; Blasco, José María (American Society for Microbiology, 2011)
Artículo / Artikulua
Bacteriological diagnosis of brucellosis is performed by culturing animal samples directly on both Farrell medium (FM) and modified Thayer-Martin medium (mTM). However, despite inhibiting most contaminating microorganisms, ... -
Estudio del sistema Wzm/Wzt en Brucella y evaluación del candidato vacunal Rev1∆wzm frente a la brucelosis ovina
(2023) Tesis doctoral / Doktoretza tesia
La brucelosis es una enfermedad zoonótica causada por bacterias del género Brucella que, además, conlleva grandes pérdidas económicas. La principal fuente de infección para el ser humano son los rumiantes, en los que la ... -
Estudios de patogénesis placentaria por Brucella y caracterización molecular de Brucella suis bv2
(2022) Tesis doctoral / Doktoretza tesiaLa brucelosis es una zoonosis mundialmente extendida con importantes repercusiones económicas y sanitarias tanto para la ganadería como para el ser humano. Existen doce especies distintas de Brucella con distinta preferencia ... -
The extradomain a of fibronectin enhances the efficacy of lipopolysaccharide defective Salmonella bacterins as vaccines in mice
San Román Aberasturi, Beatriz ; Lasa Uzcudun, Íñigo ; Andrés Cara, Damián de ; Amorena Zabalza, Beatriz ; Lasarte, Juan José; Grilló Dolset, María Jesús; Garrido, Victoria ; Muñoz Álvaro, Pilar María; Arribillaga, Laura; García Martínez, Begoña ; Andrés, Ximena de; Zabaleta, Virginia ; Mansilla, Cristina; Farrán Blanch, Inmaculada (BioMed Central, 2012)
Artículo / Artikulua
The Extradomain A from fibronectin (EDA) has an immunomodulatory role as fusion protein with viral and tumor antigens, but its effect when administered with bacteria has not been assessed. Here, we investigated the adjuvant ... -
Identification of lptA, lpxE, and lpxO, three genes involved in the remodeling of Brucella cell envelope
Conde Álvarez, Raquel; Palacios Chaves, Leyre; Gil Ramírez, Yolanda; Salvador Bescós, Miriam; Bárcena-Varela, Marina; Aragón Aranda, Beatriz; Martínez Gómez, Estrella; Zúñiga Ripa, Amaia; Miguel López, María Jesús de; Bartholomew, Toby Leigh; Hanniffy, Sean; Grilló Dolset, María Jesús; Vences Guzmán, Miguel Ángel; Bengoechea Alonso, José Antonio; Arce Gorvel, Vilma; Gorvel, Jean-Pierre; Moriyón Uría, Ignacio; Iriarte, Maite (Frontiers Media, 2018)
Artículo / Artikulua
The brucellae are facultative intracellular bacteria that cause a worldwide extended zoonosis. One of the pathogenicity mechanisms of these bacteria is their ability to avoid rapid recognition by innate immunity because ... -
In vivo monitoring of Staphylococcus aureus biofilm infections and antimicrobial therapy by [18F]fluoro-deoxyglucose–MicroPET in a mouse model
Garrido, Victoria; Collantes, María; Barberán, Montserrat; Peñuelas, Iván; Arbizu, Javier; Amorena Zabalza, Beatriz ; Grilló Dolset, María Jesús (American Society for Microbiology, 2014)
Artículo / Artikulua
A mouse model was developed for in vivo monitoring of infection and the effect of antimicrobial treatment against Staphylococcus aureus biofilms, using the [18F]fluoro-deoxyglucose–MicroPET ([18F]FDG-MicroPET) image ... -
The lipopolysaccharide core of Brucella abortus acts as a shield against innate immunity recognition
(Public Library of Science, 2012) Artículo / Artikulua
Innate immunity recognizes bacterial molecules bearing pathogen-associated molecular patterns to launch inflammatory responses leading to the activation of adaptive immunity. However, the lipopolysaccharide (LPS) of the ... -
Multidrug resistant Salmonella enterica isolated from conventional pig farms using antimicrobial agents in preventative medicine programmes
Cameron Veasa, Karla; Fraile, Lorenzo; Nappa, Sebastian; Garrido, Victoria; Grilló Dolset, María Jesús (Elsevier, 2018)
Artículo / Artikulua
A longitudinal study was conducted to investigate the presence of multidrug antimicrobial resistance (multi-AR) in Salmonella enterica in pigs reared under conventional preventative medicine programmes in Spain and the ... -
Mutants in the lipopolysaccharide of Brucella ovis are attenuated and protect against B. ovis infection in mice
Soler Lloréns, Pedro; Gil Ramírez, Yolanda; Zabalza Baranguá, Ana ; Iriarte, Maite; Conde Álvarez, Raquel; Zúñiga Ripa, Amaia; San Román Aberasturi, Beatriz ; Zygmunt, Michel; Vizcaíno, Nieves; Cloeckaert, Axel; Grilló Dolset, María Jesús; Moriyón Uría, Ignacio; López Goñi, Ignacio (BioMed Central, 2014)
Artículo / Artikulua
Brucella spp. are Gram-negative bacteria that behave as facultative intracellular parasites of a variety of mammals. This genus includes smooth (S) and rough (R) species that carry S and R lipopolysaccharides (LPS), ... -
Relationship between azithromycin susceptibility and administration efficacy for nontypeable Haemophilus influenzae respiratory infection
Euba, Begoña; Moleres Apilluelo, Javier ; Viadas Martínez, Cristina ; Barberán, Montserrat; Caballero Coronado, Lucía; Grilló Dolset, María Jesús; Bengoechea Alonso, José Antonio; Torres, Juan de; Liñares, Josefina; Leiva, José; Garmendia García, Juncal (American Society for Microbiology, 2015)
Artículo / Artikulua
Nontypeable Haemophilus influenzae (NTHI) is an opportunistic pathogen that is an important cause of acute exacerbations of chronic obstructive pulmonary disease (AECOPD). COPD is an inflammatory disease of the airways, ... -
Relative contributions of lipooligosaccharide inner and outer core modifications to nontypeable Haemophilus influenzae pathogenesis
Morey, Pau; Viadas Martínez, Cristina; Euba, Begoña; Hood, Derek W.; Barberán, Montserrat; Gil Puig, Carmen ; Grilló Dolset, María Jesús; Bengoechea Alonso, José Antonio; Garmendia García, Juncal (American Society for Microbiology, 2013)
Artículo / Artikulua
Nontypeable Haemophilus influenzae (NTHi) is a frequent commensal of the human nasopharynx that causes opportunistic infection in immunocompromised individuals. Existing evidence associates lipooligosaccharide (LOS) with ... -
Role of the Omp25/Omp31 family in outer membrane properties and virulence of Brucella ovis
(American Society for Microbiology, 2007) Artículo / Artikulua
The genes coding for the five outer membrane proteins (OMPs) of the Omp25/Omp31 family expected to be located in the outer membrane (OM) of rough virulent Brucella ovis PA were inactivated to evaluate their role in virulence ... -
Sensitivity of the ISO 6579:2002/Amd 1:2007 standard method for detection of Salmonella spp. on mesenteric lymph nodes from slaughter pigs
Mainar Jaime, Raúl Carlos; Andrés, S.; Vico, J. P.; San Román Aberasturi, Beatriz ; Garrido, Victoria ; Grilló Dolset, María Jesús (American Society for Microbiology, 2012)
Artículo / Artikulua
The ISO 6579:2002/Amd 1:2007 (ISO) standard has been the bacteriological standard method used in the European Union for the detection of Salmonella spp. in pig mesenteric lymph nodes (MLN), but there are no published ... -
Simultaneous infections by different Salmonella strains in mesenteric lymph nodes of finishing pigs
Garrido, Victoria; Sánchez Alarcón, Samanta Rita; San Román Aberasturi, Beatriz ; Zabalza Baranguá, Ana ; Díaz Tendero, Yasmín; Frutos, Cristina de; Mainar Jaime, Raúl Carlos; Grilló Dolset, María Jesús (BioMed Central, 2014)
Artículo / Artikulua
Background: Salmonellosis is a major worldwide zoonosis, and Salmonella-infected finishing pigs are considered one of the major sources of human infections in developed countries. Baseline studies on salmonellosis ...
